Your senior dog isn't old. Their cells are running out of fuel.

Give your senior dog the energy, mobility, and spark of a younger dog - in one daily dropper.

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Reated 12400+ dog parents

From $28/bottle · 90-day money-back · Free U.S. shipping over $50

Vet Formulated

EU-Made

For Dogs 4+

GMP Certified

What owners tell us after 30–60 days*

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*From 8,400 customer follow-up surveys, June–December 2025. 

These aren't lab numbers. They're what dog owners noticed in their own kitchen, on their own walks, in their own dog.

Reviewed & Approved by Dr. Helena Carter, DVM

23 years of experience in integrative veterinary medicine

"Sepili is the most complete NAD+ formula I've seen for dogs. I recommend it to my own patients."

How many of these does your dog have?

Most owners miss these signs until it's too late. If 3 or more sound familiar – your dog's cellular decline has already started.

If even half of these sound like your dog - keep reading. There's a reason it's happening, and it's not just 'old age.'

The diagnoses coming for your dog (if you don't act)

Here's what 1 in 3 senior dogs will develop in the next 3–5 years.

All four conditions share one upstream cause. Once you understand it, prevention becomes possible.

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It's not old age - 
it's a fuel crisis.

Every cell in your dog's body runs on a molecule called NAD+ (Nicotinamide Adenine Dinucleotide). It powers cellular energy, repairs DNA every day, and switches on the body's anti-aging programs.

In dogs, NAD+ levels collapse roughly 7× faster than in humans.

By the time your dog turns 7, their cellular NAD+ has already dropped 30–50%. Less fuel, less repair, less spark.

How NAD+ collapse breaks your dog (4 layers deep)

Aging is a chain of 4 failures. Most supplements fix one. The other three keep breaking.

01 NAD+ Pool Empties

No fuel for cellular energy. No repair signals. The dog slows down.
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02 Mitochondria Disappear

Cells lose their energy factories. You're now fueling a shrinking engine.
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03 The Heart Gets Strained

Restored energy means harder cardiac work. Without taurine, the heart can't keep up.
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04 Methyl Reserves Drain

Long-term NMN use depletes methyl groups. The supplement quietly stops working.
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Sepili is the only formula built to address all four – not one or two.

Introducing Sepili– the complete 4-layer formula

Most NAD+ formulas hit one layer. Sepili is the only one built for all four – at clinical doses, in a liquid your dog actually wants to eat.

NMN – Nicotinamide Mononucleotide

Direct building block for NAD+. Refuels cellular energy across muscle, brain, heart, kidneys.
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PQQ – Pyrroloquinoline Quinone

One of the few compounds known to grow new mitochondria. NMN fuels existing engines. PQQ builds more.
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Taurine

Cardioprotective amino acid. FDA-linked to dilated cardiomyopathy when deficient.
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TMG – Trimethylglycine (Betaine)

Replaces the methyl groups NMN uses up over time. The reason Sepili keeps working long-term.
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Just 6 things in the bottle

4 actives that do the cellular work. 2 carriers that make them edible. That's it. No fillers, no preservatives, no hidden additives.

Three things no other dog supplement does

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Ready to get your dog back?

Skip the rest. Start the 90-day reset today.

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90-day money-back  ·  Free U.S. shipping over $50

Already doing the work? Sepili makes it count.

Most senior-dog supplements treat one symptom at a time. Sepili works on the cellular cause – and stacks with what you already give.

Won't your dog just spit it out?

Most NAD+ formulas hit one layer. Sepili is the only one built for all four – at clinical doses, in a liquid your dog actually wants to eat.

What's NOT in Sepili (and why that matters)

Most dog supplements look clean on the front label. Flip them over. The carrier ingredients tell the real story –

 and most of them shouldn't be in a daily product your dog takes for life.

Formulated With Veterinary Science, Not Marketing Buzzwords

Dr. Helena Carter, DVM

Lead Veterinary Advisor

Dr. Helena Carter has spent 23 years practicing integrative veterinary medicine, with a focus on senior dog longevity and mobility. She reviewed every ingredient, every dose, and every claim in this formula before launch.

 

Most NAD+ supplements for dogs treat the surface symptoms. Sepili is the first one I've seen built around the whole cascade – and dosed correctly. It's what I give my own dog.

Real dogs. Real owners. Real changes.

Sent in by Sepili customers – not paid actors, not stock photos.
Sepili– the complete 4-layer liquid formula for aging dogs
Sepili– the complete 4-layer liquid formula for aging dogs
Sepili– the complete 4-layer liquid formula for aging dogs
Sepili– the complete 4-layer liquid formula for aging dogs

4.83 BASED ON 12,400+ DOG PARENTS

Sepili – the complete 4-layer liquid formula for aging dogs

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The 90-Day Guarantee

If you don't see real change in your dog within 90 days, we'll refund every cent. Hassle-free, no return shipping.

Is Sepili safe for my dog?

Yes. All four ingredients are well-studied in dogs, dosed by your dog's body weight. Made in an EU-approved, GMP-certified facility. Third-party tested every batch. Talk to your vet first if your dog is on prescription medication.

How long until I see results?

Most owners see first signs within 30 days — less stiffness, more energy, more eye contact. Full transformation by week 12. Backed by a 90-day money-back guarantee, so you have time to see real change.

What if my dog hates the taste?

Very rare. 85% of dogs choose food with our flavor base FIRST in independent testing. Real hydrolyzed chicken liver — not artificial. If your dog refuses it, our 90-day money-back guarantee covers it. No return needed.

Can I give Sepili alongside my dog's other medications?

Sepili is a supplement, not a medication. It works alongside joint chews, fish oil, and most prescriptions. If your dog is on heart, blood pressure, or anti-inflammatory medication (like Librela or Anipryl), confirm with your vet first.

How does the subscription work? Can I cancel anytime?

Yes. Cancel anytime from your dashboard — no questions asked, no fees. Subscribe and save 10%, ships free in the U.S. every 30, 60, or 90 days. Pause, skip, or change frequency whenever you want.

We're so sure, we'll pay you if we're wrong

If you don't see a real, visible change in your dog within 90 days - more energy, easier movement, sharper presence - we'll refund every cent. 

No questions. No return shipping. No fine print. 

We can promise this because we've watched the formula work on hundreds of dogs already. But the only opinion that matters is yours, watching your dog.

Sepili – the complete 4-layer liquid formula for aging dogs

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